Identification of DUSP4/6 overexpression as a potential rheostat to NRAS-induced hepatocarcinogenesi...
Identification of DUSP4/6 overexpression as a potential rheostat to NRAS-induced hepatocarcinogenesis
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Upregulation of the mitogen-activated protein kinase (MAPK) cascade is common in hepatocellular carcinoma (HCC). Neuroblastoma RAS viral oncogene homolog (NRAS) is mutated in a small percentage of HCC and is hitherto considered insufficient for hepatocarcinogenesis. We aimed to characterize the process of N-Ras-dependent carcinogenesis in the liver...
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Full title
Identification of DUSP4/6 overexpression as a potential rheostat to NRAS-induced hepatocarcinogenesis
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TN_cdi_doaj_primary_oai_doaj_org_article_de2d353499314a8ba83c34a067ed7892
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_de2d353499314a8ba83c34a067ed7892
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ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-023-11577-9
