Transmission of atypical bovine prions to mice transgenic for human prion protein
Transmission of atypical bovine prions to mice transgenic for human prion protein
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Publisher
United States: U.S. National Center for Infectious Diseases
Journal title
Language
English
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Publisher
United States: U.S. National Center for Infectious Diseases
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To assess risk for cattle-to-human transmission of prions that cause uncommon forms of bovine spongiform encephalopathy (BSE), we inoculated mice expressing human PrP Met129 with field isolates. Unlike classical BSE agent, L-type prions appeared to propagate in these mice with no obvious transmission barrier. H-type prions failed to infect the mice...
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Full title
Transmission of atypical bovine prions to mice transgenic for human prion protein
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_de2e1545fe5f4d73a1188ea0c5e8c0dd
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_de2e1545fe5f4d73a1188ea0c5e8c0dd
Other Identifiers
ISSN
1080-6040
E-ISSN
1080-6059
DOI
10.3201/eid1412.080941
