TSA attenuates the progression of c-Myc-driven hepatocarcinogenesis by pAKT-ADH4 pathway
TSA attenuates the progression of c-Myc-driven hepatocarcinogenesis by pAKT-ADH4 pathway
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Author / Creator
Liu, Yang , Yu, Juan , An, Xiaotong , Rao, Huiling , Qiu, Zhenpeng , Ke, Jing , Wu, Lun , Zhu, Zhengpeng , Deng, Haojun , Wu, Fuyun , Zhang, Zhaoyang and Li, Shan
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Hepatocellular carcinoma (HCC) is the primary malignant tumor of the liver. c-Myc is one of the most common oncogenes in clinical settings, and amplified levels of c-Myc are frequently found in HCC. Histone deacetylase inhibitors (HDACi), such as Trichostatin A (TSA), hold enormous promise for the treatment of HCC. However, the potential and mechan...
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Full title
TSA attenuates the progression of c-Myc-driven hepatocarcinogenesis by pAKT-ADH4 pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_de5f34ac36574de6a20653f5838459c8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_de5f34ac36574de6a20653f5838459c8
Other Identifiers
ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-024-12781-x
