Oncogene-specific differences in tumor mutational burden, PD-L1 expression, and outcomes from immuno...
Oncogene-specific differences in tumor mutational burden, PD-L1 expression, and outcomes from immunotherapy in non-small cell lung cancer
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Author / Creator
Negrao, Marcelo V , Skoulidis, Ferdinandos , Montesion, Meagan , Schulze, Katja , Bara, Ilze , Shen, Vincent , Xu, Hao , Hu, Sylvia , Sui, Dawen , Elamin, Yasir Y , Le, Xiuning , Goldberg, Michael E , Murugesan, Karthikeyan , Wu, Chang-Jiun , Zhang, Jianhua , Barreto, David S , Robichaux, Jacqulyne P , Reuben, Alexandre , Cascone, Tina , Gay, Carl M , Mitchell, Kyle G , Hong, Lingzhi , Rinsurongkawong, Waree , Roth, Jack A , Swisher, Stephen G , Lee, Jack , Tsao, Anne , Papadimitrakopoulou, Vassiliki , Gibbons, Don L , Glisson, Bonnie S , Singal, Gaurav , Miller, Vincent A , Alexander, Brian , Frampton, Garrett , Albacker, Lee A , Shames, David , Zhang, Jianjun and Heymach, John V
Publisher
England: BMJ Publishing Group LTD
Journal title
Language
English
Formats
Publication information
Publisher
England: BMJ Publishing Group LTD
Subjects
More information
Scope and Contents
Contents
BackgroundNon-small cell lung cancer (NSCLC) patients bearing targetable oncogene alterations typically derive limited benefit from immune checkpoint blockade (ICB), which has been attributed to low tumor mutation burden (TMB) and/or PD-L1 levels. We investigated oncogene-specific differences in these markers and clinical outcome.MethodsThree cohor...
Alternative Titles
Full title
Oncogene-specific differences in tumor mutational burden, PD-L1 expression, and outcomes from immunotherapy in non-small cell lung cancer
Authors, Artists and Contributors
Author / Creator
Skoulidis, Ferdinandos
Montesion, Meagan
Schulze, Katja
Bara, Ilze
Shen, Vincent
Xu, Hao
Hu, Sylvia
Sui, Dawen
Elamin, Yasir Y
Le, Xiuning
Goldberg, Michael E
Murugesan, Karthikeyan
Wu, Chang-Jiun
Zhang, Jianhua
Barreto, David S
Robichaux, Jacqulyne P
Reuben, Alexandre
Cascone, Tina
Gay, Carl M
Mitchell, Kyle G
Hong, Lingzhi
Rinsurongkawong, Waree
Roth, Jack A
Swisher, Stephen G
Lee, Jack
Tsao, Anne
Papadimitrakopoulou, Vassiliki
Gibbons, Don L
Glisson, Bonnie S
Singal, Gaurav
Miller, Vincent A
Alexander, Brian
Frampton, Garrett
Albacker, Lee A
Shames, David
Zhang, Jianjun
Heymach, John V
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_deb634044c5641f5a4d7746a8b39b598
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_deb634044c5641f5a4d7746a8b39b598
Other Identifiers
ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2021-002891
