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ArticlesPeer ReviewedFull Text
Co-occurring genomic alterations in non-small-cell lung cancer biology and therapy
Author / Creator:Skoulidis, Ferdinandos ; Heymach, John V.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2019-09, Vol.19 (9), p.495-509
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ArticlesPeer ReviewedFull Text
Emerging therapeutics and evolving assessment criteria for intracranial metastases in patients with oncogene-driven non-small-cell lung cancer
Author / Creator:Pan, Kelsey ; Concannon, Kyle ; Li, Jing ; Zhang, Jianjun ; Heymach, John V. ; Le, Xiuning
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Clinical oncology, 2023-10, Vol.20 (10), p.716-732
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ArticlesPeer ReviewedFull Text
Perioperative Durvalumab for Resectable Non–Small-Cell Lung Cancer
Author / Creator:Heymach, John V. ; Harpole, David ; Mitsudomi, Tetsuya ; Taube, Janis M. ; Galffy, Gabriella ; Hochmair, Maximilian ; Winder, Thomas ; Zukov, Ruslan ; Garbaos, Gabriel ; Gao, Shugeng ; Kuroda, Hiroaki ; Ostoros, Gyula ; Tran, Tho V. ; You, Jian ; Lee, Kang-Yun ; Antonuzzo, Lorenzo ; Papai-Szekely, Zsolt ; Akamatsu, Hiroaki ; Biswas, Bivas ; Spira, Alexander ; Crawford, Jeffrey ; Le, Ha T. ; Aperghis, Mike ; Doherty, Gary J. ; Mann, Helen ; Fouad, Tamer M. ; Reck, Martin
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2023-11, Vol.389 (18), p.1672-1684
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ArticlesPeer ReviewedFull Text
Mechanisms and clinical activity of an EGFR and HER2 exon 20–selective kinase inhibitor in non–small cell lung cancer
Author / Creator:Robichaux, Jacqulyne P. ; Elamin, Yasir Y. ; Tan, Zhi ; Carter, Brett W. ; Zhang, Shuxing ; Liu, Shengwu ; Li, Shuai ; Chen, Ting ; Poteete, Alissa ; Estrada-Bernal, Adriana ; Le, Anh T. ; Truini, Anna ; Nilsson, Monique B. ; Sun, Huiying ; Roarty, Emily ; Goldberg, Sarah B. ; Brahmer, Julie R. ; Altan, Mehmet ; Lu, Charles ; Papadimitrakopoulou, Vassiliki ; Politi, Katerina ; Doebele, Robert C. ; Wong, Kwok-Kin ; Heymach, John V.
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2018-05, Vol.24 (5), p.638-646
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ArticlesPeer ReviewedFull Text
Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance
Author / Creator:Chu, Yanshuo ; Dai, Enyu ; Li, Yating ; Han, Guangchun ; Pei, Guangsheng ; Ingram, Davis R. ; Thakkar, Krupa ; Qin, Jiang-Jiang ; Dang, Minghao ; Le, Xiuning ; Hu, Can ; Deng, Qing ; Sinjab, Ansam ; Gupta, Pravesh ; Wang, Ruiping ; Hao, Dapeng ; Peng, Fuduan ; Yan, Xinmiao ; Liu, Yunhe ; Song, Shumei ; Zhang, Shaojun ; Heymach, John V. ; Reuben, Alexandre ; Elamin, Yasir Y. ; Pizzi, Melissa P. ; Lu, Yang ; Lazcano, Rossana ; Hu, Jian ; Li, Mingyao ; Curran, Michael ; Futreal, Andrew ; Maitra, Anirban ; Jazaeri, Amir A. ; Ajani, Jaffer A. ; Swanton, Charles ; Cheng, Xiang-Dong ; Abbas, Hussein A. ; Gillison, Maura ; Bhat, Krishna ; Lazar, Alexander J. ; Green, Michael ; Litchfield, Kevin ; Kadara, Humam ; Yee, Cassian ; Wang, Linghua
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2023-06, Vol.29 (6), p.1550-1562
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ArticlesPeer ReviewedFull Text
Antibody-drug conjugates in lung cancer: dawn of a new era?
Author / Creator:Coleman, Niamh ; Yap, Timothy A. ; Heymach, John V. ; Meric-Bernstam, Funda ; Le, Xiuning
Publisher:London: Nature Publishing Group UK
Journal title:NPJ precision oncology, 2023-01, Vol.7 (1), p.5-5, Article 5
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ArticlesPeer ReviewedFull Text
Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing
Author / Creator:Zhang, Jianjun ; Fujimoto, Junya ; Zhang, Jianhua ; Wedge, David C. ; Song, Xingzhi ; Zhang, Jiexin ; Seth, Sahil ; Chow, Chi-Wan ; Cao, Yu ; Gumbs, Curtis ; Gold, Kathryn A. ; Kalhor, Neda ; Little, Latasha ; Mahadeshwar, Harshad ; Moran, Cesar ; Protopopov, Alexei ; Sun, Huandong ; Tang, Jiabin ; Wu, Xifeng ; Ye, Yuanqing ; William, William N. ; Lee, J. Jack ; Heymach, John V. ; Hong, Waun Ki ; Swisher, Stephen ; Wistuba, Ignacio I. ; Futreal, P. Andrew
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2014-10, Vol.346 (6206), p.256-260
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ArticlesPeer ReviewedFull Text
CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells
Author / Creator:Kim, Jiyeon ; Hu, Zeping ; Cai, Ling ; Li, Kailong ; Choi, Eunhee ; Faubert, Brandon ; Bezwada, Divya ; Rodriguez-Canales, Jaime ; Villalobos, Pamela ; Lin, Yu-Fen ; Ni, Min ; Huffman, Kenneth E. ; Girard, Luc ; Byers, Lauren A. ; Unsal-Kacmaz, Keziban ; Peña, Christopher G. ; Heymach, John V. ; Wauters, Els ; Vansteenkiste, Johan ; Castrillon, Diego H. ; Chen, Benjamin P. C. ; Wistuba, Ignacio ; Lambrechts, Diether ; Xu, Jian ; Minna, John D. ; DeBerardinis, Ralph J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-06, Vol.546 (7656), p.168-172
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ArticlesPeer ReviewedFull Text
Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer
Author / Creator:Nong, Jingying ; Gong, Yuhua ; Guan, Yanfang ; Yi, Xin ; Yi, Yuting ; Chang, Lianpeng ; Yang, Ling ; Lv, Jialin ; Guo, Zhirong ; Jia, Hongyan ; Chu, Yuxing ; Liu, Tao ; Chen, Ming ; Byers, Lauren ; Roarty, Emily ; Lam, Vincent K. ; Papadimitrakopoulou, Vassiliki A. ; Wistuba, Ignacio ; Heymach, John V. ; Glisson, Bonnie ; Liao, Zhongxing ; Lee, J. Jack ; Futreal, P. Andrew ; Zhang, Shucai ; Xia, Xuefeng ; Zhang, Jianjun ; Wang, Jinghui
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-08, Vol.9 (1), p.3114-8, Article 3114
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ArticlesPeer ReviewedFull Text
A pan-cancer proteomic perspective on The Cancer Genome Atlas
Author / Creator:Akbani, Rehan ; Ng, Patrick Kwok Shing ; Werner, Henrica M. J. ; Shahmoradgoli, Maria ; Zhang, Fan ; Ju, Zhenlin ; Liu, Wenbin ; Yang, Ji-Yeon ; Yoshihara, Kosuke ; Li, Jun ; Ling, Shiyun ; Seviour, Elena G. ; Ram, Prahlad T. ; Minna, John D. ; Diao, Lixia ; Tong, Pan ; Heymach, John V. ; Hill, Steven M. ; Dondelinger, Frank ; Städler, Nicolas ; Byers, Lauren A. ; Meric-Bernstam, Funda ; Weinstein, John N. ; Broom, Bradley M. ; Verhaak, Roeland G. W. ; Liang, Han ; Mukherjee, Sach ; Lu, Yiling ; Mills, Gordon B.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-05, Vol.5 (1), p.3887-3887, Article 3887
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ArticlesPeer ReviewedFull Text
Therapeutic Delivery of miR-200c Enhances Radiosensitivity in Lung Cancer
Author / Creator:Cortez, Maria Angelica ; Valdecanas, David ; Zhang, Xiaochun ; Zhan, Yanai ; Bhardwaj, Vikas ; Calin, George A ; Komaki, Ritsuko ; Giri, Dipak K ; Quini, Caio C ; Wolfe, Tatiana ; Peltier, Heidi J ; Bader, Andreas G ; Heymach, John V ; Meyn, Raymond E ; Welsh, James W
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2014-08, Vol.22 (8), p.1494-1503
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ArticlesPeer ReviewedFull Text
Vandetanib plus docetaxel versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer (ZODIAC): a double-blind, randomised, phase 3 trial
Author / Creator:Herbst, Roy S, Prof ; Sun, Yan, MD ; Eberhardt, Wilfried EE, MD ; Germonpré, Paul, MD ; Saijo, Nagahiro, Prof ; Zhou, Caicun, MD ; Wang, Jie, MD ; Li, Longyun, MD ; Kabbinavar, Fairooz, MD ; Ichinose, Yukito, MD ; Qin, Shukui, MD ; Zhang, Li, MD ; Biesma, Bonne, MD ; Heymach, John V, MD ; Langmuir, Peter, MD ; Kennedy, Sarah J, MSc ; Tada, Hiroomi, MD ; Johnson, Bruce E, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2010-07, Vol.11 (7), p.619-626
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ArticlesPeer ReviewedFull Text
Prognostic or predictive plasma cytokines and angiogenic factors for patients treated with pazopanib for metastatic renal-cell cancer: a retrospective analysis of phase 2 and phase 3 trials
Author / Creator:Tran, Hai T, PharmD ; Liu, Yuan, PhD ; Zurita, Amado J, MD ; Lin, Ying, PhD ; Baker-Neblett, Katherine L, MBA ; Martin, Anne-Marie, PhD ; Figlin, Robert A, MD ; Hutson, Thomas E, DO ; Sternberg, Cora N, MD ; Amado, Rafael G, MD ; Pandite, Lini N, MD ; Heymach, John V, Dr
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2012-08, Vol.13 (8), p.827-837
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ArticlesPeer ReviewedFull Text
Functional characterization of CLPTM1L as a lung cancer risk candidate gene in the 5p15.33 locus
Author / Creator:James, Michael A ; Wen, Weidong ; Wang, Yian ; Byers, Lauren A ; Heymach, John V ; Coombes, Kevin R ; Girard, Luc ; Minna, John ; You, Ming
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-06, Vol.7 (6), p.e36116
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ArticlesPeer ReviewedFull Text
Activation of the PI3K/mTOR Pathway following PARP Inhibition in Small Cell Lung Cancer
Author / Creator:Cardnell, Robert J ; Feng, Ying ; Mukherjee, Seema ; Diao, Lixia ; Tong, Pan ; Stewart, C Allison ; Masrorpour, Fatemeh ; Fan, YouHong ; Nilsson, Monique ; Shen, Yuqiao ; Heymach, John V ; Wang, Jing ; Byers, Lauren A
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-04, Vol.11 (4), p.e0152584-e0152584
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ArticlesPeer ReviewedFull Text
The association of alternate VEGF ligands with resistance to anti-VEGF therapy in metastatic colorectal cancer
Author / Creator:Lieu, Christopher H ; Tran, Hai ; Jiang, Zhi-Qin ; Mao, Muling ; Overman, Michael J ; Lin, E ; Eng, Cathy ; Morris, Jeffrey ; Ellis, Lee ; Heymach, John V ; Kopetz, Scott
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-10, Vol.8 (10), p.e77117-e77117
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ArticlesPeer ReviewedFull Text
Molecular classification and biomarkers of outcome with immunotherapy in extensive-stage small-cell lung cancer: analyses of the CASPIAN phase 3 study
Author / Creator:Xie, Mingchao ; Vuko, Miljenka ; Rodriguez-Canales, Jaime ; Zimmermann, Johannes ; Schick, Markus ; O'Brien, Cathy ; Paz-Ares, Luis ; Goldman, Jonathan W ; Garassino, Marina Chiara ; Gay, Carl M ; Heymach, John V ; Jiang, Haiyi ; Barrett, J Carl ; Stewart, Ross A ; Lai, Zhongwu ; Byers, Lauren A ; Rudin, Charles M ; Shrestha, Yashaswi
Publisher:England: BioMed Central Ltd
Journal title:Molecular cancer, 2024-05, Vol.23 (1), p.115-17, Article 115
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ArticlesPeer ReviewedFull Text
Influence of low-dose radiation on abscopal responses in patients receiving high-dose radiation and immunotherapy
Author / Creator:Menon, Hari ; Chen, Dawei ; Ramapriyan, Rishab ; Verma, Vivek ; Barsoumian, Hampartsoum B ; Cushman, Taylor R ; Younes, Ahmed I ; Cortez, Maria A ; Erasmus, Jeremy J ; de Groot, Patricia ; Carter, Brett W ; Hong, David S ; Glitza, Isabella C ; Ferrarotto, Renata ; Altan, Mehmet ; Diab, Adi ; Chun, Stephen G ; Heymach, John V ; Tang, Chad ; Nguyen, Quynh N ; Welsh, James W
Publisher:England: BioMed Central Ltd
Journal title:Journal for immunotherapy of cancer, 2019-09, Vol.7 (1), p.237-237, Article 237
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ArticlesPeer ReviewedFull Text
Effect of neoadjuvant chemotherapy on the immune microenvironment in non-small cell lung carcinomas as determined by multiplex immunofluorescence and image analysis approaches
Author / Creator:Parra, Edwin R ; Villalobos, Pamela ; Behrens, Carmen ; Jiang, Mei ; Pataer, Apar ; Swisher, Stephen G ; William, Jr, William N ; Zhang, Jiexin ; Lee, Jack ; Cascone, Tina ; Heymach, John V ; Forget, Marie-Andrée ; Haymaker, Cara ; Bernatchez, Chantale ; Kalhor, Neda ; Weissferdt, Annikka ; Moran, Cesar ; Zhang, Jianjun ; Vaporciyan, Ara ; Gibbons, Don L ; Sepesi, Boris ; Wistuba, Ignacio I
Publisher:England: BioMed Central Ltd
Journal title:Journal for immunotherapy of cancer, 2018-06, Vol.6 (1), p.48-48, Article 48
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Newsletter articlesFull Text
Heymach John V, Wang Jing, Byers Lauren Averett, Coombes Kevin R, Minna John D, Girard Luc and Board of Regents File United States Patent Application for EMT Signatures and Predictive Markers and Meth...
Publisher:New Delhi: Pedia Content Solutions Pvt. Ltd
Journal title:Global IP News. Medical Patent News, 2014
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Co-occurring genomic alterations in non-small-cell lung cancer biology and therapy

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Emerging therapeutics and evolving assessment criteria for intracranial metastases in patients with oncogene-driven non-small-cell lung cancer

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Perioperative Durvalumab for Resectable Non–Small-Cell Lung Cancer

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Mechanisms and clinical activity of an EGFR and HER2 exon 20–selective kinase inhibitor in non–small cell lung cancer

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Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance

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Antibody-drug conjugates in lung cancer: dawn of a new era?

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Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing

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CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells

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Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer

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A pan-cancer proteomic perspective on The Cancer Genome Atlas

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Therapeutic Delivery of miR-200c Enhances Radiosensitivity in Lung Cancer

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Vandetanib plus docetaxel versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer (ZODIAC): a double-blind, randomised, phase 3 trial

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Prognostic or predictive plasma cytokines and angiogenic factors for patients treated with pazopanib for metastatic renal-cell cancer: a retrospective analysis of phase 2 and phase 3 trials

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Functional characterization of CLPTM1L as a lung cancer risk candidate gene in the 5p15.33 locus

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Activation of the PI3K/mTOR Pathway following PARP Inhibition in Small Cell Lung Cancer

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The association of alternate VEGF ligands with resistance to anti-VEGF therapy in metastatic colorectal cancer

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Molecular classification and biomarkers of outcome with immunotherapy in extensive-stage small-cell lung cancer: analyses of the CASPIAN phase 3 study

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Influence of low-dose radiation on abscopal responses in patients receiving high-dose radiation and immunotherapy

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Effect of neoadjuvant chemotherapy on the immune microenvironment in non-small cell lung carcinomas as determined by multiplex immunofluorescence and image analysis approaches

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Heymach John V, Wang Jing, Byers Lauren Averett, Coombes Kevin R, Minna John D, Girard Luc and Board of Regents File United States Patent Application for EMT Signatures and Predictive Markers and Meth...

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