Bank vole prion protein extends the use of RT-QuIC assays to detect prions in a range of inherited p...
Bank vole prion protein extends the use of RT-QuIC assays to detect prions in a range of inherited prion diseases
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The cerebrospinal fluid (CSF) real-time quaking-induced conversion assay (RT-QuIC) is an ultrasensitive prion amyloid seeding assay for diagnosis of sporadic Creutzfeldt–Jakob disease (CJD) but several prion strains remain unexplored or resistant to conversion with commonly used recombinant prion protein (rPrP) substrates. Here, bank vole (BV) rPrP...
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Bank vole prion protein extends the use of RT-QuIC assays to detect prions in a range of inherited prion diseases
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TN_cdi_doaj_primary_oai_doaj_org_article_df04884ac887422694fcb1d5a25cc4e0
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_df04884ac887422694fcb1d5a25cc4e0
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-84527-9
