Oral administration of repurposed drug targeting Cyp46A1 increases survival times of prion infected...
Oral administration of repurposed drug targeting Cyp46A1 increases survival times of prion infected mice
About this item
Full title
Author / Creator
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Prion diseases are fatal, infectious, and incurable neurodegenerative disorders caused by misfolding of the cellular prion protein (PrP
) into the infectious isoform (PrP
). In humans, there are sporadic, genetic and infectious etiologies, with sporadic Creutzfeldt-Jakob disease (sCJD) being the most common form. Currently, no treatment is av...
Alternative Titles
Full title
Oral administration of repurposed drug targeting Cyp46A1 increases survival times of prion infected mice
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_df386e613c3148bea1070a9c620720db
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_df386e613c3148bea1070a9c620720db
Other Identifiers
ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-021-01162-1
