Melatonin-mediated mitophagy protects against early brain injury after subarachnoid hemorrhage throu...
Melatonin-mediated mitophagy protects against early brain injury after subarachnoid hemorrhage through inhibition of NLRP3 inflammasome activation
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Author / Creator
Cao, Shenglong , Shrestha, Sudeep , Li, Jianru , Yu, Xiaobo , Chen, Jingyin , Yan, Feng , Ying, Guangyu , Gu, Chi , Wang, Lin and Chen, Gao
Publisher
London: Nature Publishing Group UK
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Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
The NLRP3 inflammasome is activated in the early period following subarachnoid hemorrhage(SAH), resulting in inflammatory responses. Recent studies have shown that activation of NLRP3 inflammasome is suppressed by autophagy, but the potential mechanism is unclear. In this study, we examined whether mitophagy was involved in the beneficial effect of...
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Full title
Melatonin-mediated mitophagy protects against early brain injury after subarachnoid hemorrhage through inhibition of NLRP3 inflammasome activation
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TN_cdi_doaj_primary_oai_doaj_org_article_e05b90dc0e4b45db8f8fd44afcfb68cd
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e05b90dc0e4b45db8f8fd44afcfb68cd
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-02679-z
