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SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replicatio...

SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replicatio...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e05cdc1398a34aa49f53b13c0a5c14a8

SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication

About this item

Full title

SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2023-08, Vol.13 (1), p.14086-14086, Article 14086

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

COVID-19, caused by SARS-CoV-2, is a respiratory disease associated with inflammation and endotheliitis. Mechanisms underling inflammatory processes are unclear, but angiotensin converting enzyme 2 (ACE2), the receptor which binds the spike protein of SARS-CoV-2 may be important. Here we investigated whether spike protein binding to ACE2 induces in...

Alternative Titles

Full title

SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e05cdc1398a34aa49f53b13c0a5c14a8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e05cdc1398a34aa49f53b13c0a5c14a8

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-023-41115-3

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