Human Cytomegalovirus Inhibits the PARsylation Activity of Tankyrase—A Potential Strategy for Suppre...
Human Cytomegalovirus Inhibits the PARsylation Activity of Tankyrase—A Potential Strategy for Suppression of the Wnt Pathway
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Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Human cytomegalovirus (HCMV) was reported to downregulate the Wnt/β-catenin pathway. Induction of Axin1, the negative regulator of the Wnt pathway, has been reported as an important mechanism for inhibition of β-catenin. Since Tankyrase (TNKS) negatively regulates Axin1, we investigated the effect of HCMV on TNKS expression and poly-ADP ribose poly...
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Full title
Human Cytomegalovirus Inhibits the PARsylation Activity of Tankyrase—A Potential Strategy for Suppression of the Wnt Pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_e06b6944838e43ebb5962a683b0ebe75
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e06b6944838e43ebb5962a683b0ebe75
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ISSN
1999-4915
E-ISSN
1999-4915
DOI
10.3390/v8010008
