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ArticlesPeer ReviewedFull Text
Structural basis of tankyrase activation by polymerization
Author / Creator:Pillay, Nisha ; Mariotti, Laura ; Zaleska, Mariola ; Inian, Oviya ; Jessop, Matthew ; Hibbs, Sam ; Desfosses, Ambroise ; Hopkins, Paul C. R. ; Templeton, Catherine M. ; Beuron, Fabienne ; Morris, Edward P. ; Guettler, Sebastian
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2022-12, Vol.612 (7938), p.162-169
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Whole proteome analysis of human tankyrase knockout cells reveals targets of tankyrase-mediated degradation
Author / Creator:Bhardwaj, Amit ; Yang, Yanling ; Ueberheide, Beatrix ; Smith, Susan
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-12, Vol.8 (1), p.2214-13, Article 2214
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RK‐287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model
Author / Creator:Mizutani, Anna ; Yashiroda, Yoko ; Muramatsu, Yukiko ; Yoshida, Haruka ; Chikada, Tsubasa ; Tsumura, Takeshi ; Okue, Masayuki ; Shirai, Fumiyuki ; Fukami, Takehiro ; Yoshida, Minoru ; Seimiya, Hiroyuki
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2018-12, Vol.109 (12), p.4003-4014
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Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
Author / Creator:Huang, Shih-Min A. ; Mishina, Yuji M. ; Liu, Shanming ; Cheung, Atwood ; Stegmeier, Frank ; Michaud, Gregory A. ; Charlat, Olga ; Wiellette, Elizabeth ; Zhang, Yue ; Wiessner, Stephanie ; Hild, Marc ; Shi, Xiaoying ; Wilson, Christopher J. ; Mickanin, Craig ; Myer, Vic ; Fazal, Aleem ; Tomlinson, Ronald ; Serluca, Fabrizio ; Shao, Wenlin ; Cheng, Hong ; Shultz, Michael ; Rau, Christina ; Schirle, Markus ; Schlegl, Judith ; Ghidelli, Sonja ; Fawell, Stephen ; Lu, Chris ; Curtis, Daniel ; Kirschner, Marc W. ; Lengauer, Christoph ; Finan, Peter M. ; Tallarico, John A. ; Bouwmeester, Tewis ; Porter, Jeffery A. ; Bauer, Andreas ; Cong, Feng
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2009-10, Vol.461 (7264), p.614-620
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Novel insight into the function of tankyrase (Review)
Author / Creator:Kim, Mi
Publisher:Greece: Spandidos Publications
Journal title:Oncology letters, 2018-12, Vol.16 (6), p.6895-6902
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Tankyrase-targeted therapeutics: expanding opportunities in the PARP family
Author / Creator:Riffell, Jenna L. ; Lord, Christopher J. ; Ashworth, Alan
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Drug discovery, 2012-12, Vol.11 (12), p.923-936
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Tankyrase Inhibitors Stimulate the Ability of Tankyrases to Bind Axin and Drive Assembly of β-Catenin Degradation-Competent Axin Puncta
Author / Creator:Martino-Echarri, Estefania ; Brocardo, Mariana G. ; Mills, Kate M. ; Henderson, Beric R.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-03, Vol.11 (3), p.e0150484-e0150484
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Tankyrase inhibition promotes endocrine commitment of hPSC-derived pancreatic progenitors
Author / Creator:Poon, Frankie ; Sambathkumar, Rangarajan ; Korytnikov, Roman ; Aghazadeh, Yasaman ; Oakie, Amanda ; Misra, Paraish S. ; Sarangi, Farida ; Nostro, M. Cristina
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-10, Vol.15 (1), p.8754-16, Article 8754
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Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors
Author / Creator:Wahlberg, Elisabet ; Karlberg, Tobias ; Kouznetsova, Ekaterina ; Markova, Natalia ; Macchiarulo, Antonio ; Thorsell, Ann-Gerd ; Pol, Ewa ; Frostell, Åsa ; Ekblad, Torun ; Öncü, Delal ; Kull, Björn ; Robertson, Graeme Michael ; Pellicciari, Roberto ; Schüler, Herwig ; Weigelt, Johan
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2012-03, Vol.30 (3), p.283-288
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Multiple E3 ligases control tankyrase stability and function
Author / Creator:Perrard, Jerome ; Smith, Susan
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-11, Vol.14 (1), p.7208-17, Article 7208
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Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling
Author / Creator:Li, Nan ; Wang, Yifan ; Neri, Shinya ; Zhen, Yuanli ; Fong, Lon Wolf R. ; Qiao, Yawei ; Li, Xu ; Chen, Zhen ; Stephan, Clifford ; Deng, Weiye ; Ye, Rui ; Jiang, Wen ; Zhang, Shuxing ; Yu, Yonghao ; Hung, Mien-Chie ; Chen, Junjie ; Lin, Steven H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-09, Vol.10 (1), p.4363-14, Article 4363
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Tankyrase inhibition sensitizes cells to CDK4 blockade
Author / Creator:Foronda, Miguel ; Tarumoto, Yusuke ; Schatoff, Emma M. ; Leach, Benjamin I. ; Diaz, Bianca J. ; Zimmerman, Jill ; Goswami, Sukanya ; Shusterman, Michael ; Vakoc, Christopher R. ; Dow, Lukas E.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-12, Vol.14 (12), p.e0226645-e0226645
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Tankyrase represses autoinflammation through the attenuation of TLR2 signaling
Author / Creator:Matsumoto, Yoshinori ; Dimitriou, Ioannis D. ; La Rose, Jose ; Lim, Melissa ; Camilleri, Susan ; Law, Napoleon ; Adissu, Hibret A. ; Tong, Jiefei ; Moran, Michael F. ; Chruscinski, Andrzej ; He, Fang ; Asano, Yosuke ; Katsuyama, Takayuki ; Sada, Ken-ei ; Wada, Jun ; Rottapel, Robert
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2022-04, Vol.132 (7)
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Crystal structure of a Tankyrase-Axin complex and its implications for Axin turnover and Tankyrase substrate recruitment
Author / Creator:Morrone, Seamus ; Cheng, Zhihong ; Moon, Randall T ; Cong, Feng ; Xu, Wenqing
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-01, Vol.109 (5), p.1500-1505
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3D-QSAR, Docking, ADME/Tox studies on Flavone analogs reveal anticancer activity through Tankyrase inhibition
Author / Creator:Alam, Sarfaraz ; Khan, Feroz
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-04, Vol.9 (1), p.5414, Article 5414
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Tankyrase: a promising therapeutic target with pleiotropic action
Author / Creator:Sagathia, Vrunda ; Patel, Chirag ; Beladiya, Jayesh ; Patel, Sandip ; Sheth, Devang ; Shah, Gaurang
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Naunyn-Schmiedeberg's archives of pharmacology, 2023-12, Vol.396 (12), p.3363-3374
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Tankyrase inhibition ameliorates lipid disorder via suppression of PGC-1α PARylation in db/db mice
Author / Creator:Wang, Hong ; Kuusela, Sara ; Rinnankoski-Tuikka, Rita ; Dumont, Vincent ; Bouslama, Rim ; Ramadan, Usama Abo ; Waaler, Jo ; Linden, Anni-Maija ; Chi, Nai-Wen ; Krauss, Stefan ; Pirinen, Eija ; Lehtonen, Sanna
Publisher:London: Nature Publishing Group UK
Journal title:International Journal of Obesity, 2020-08, Vol.44 (8), p.1691-1702
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2-Phenylquinazolinones as dual-activity tankyrase-kinase inhibitors
Author / Creator:Nkizinkiko, Yves ; Desantis, Jenny ; Koivunen, Jarkko ; Haikarainen, Teemu ; Murthy, Sudarshan ; Sancineto, Luca ; Massari, Serena ; Ianni, Federica ; Obaji, Ezeogo ; Loza, Maria I. ; Pihlajaniemi, Taina ; Brea, Jose ; Tabarrini, Oriana ; Lehtiö, Lari
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-01, Vol.8 (1), p.1680-10, Article 1680
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Vascular progenitors generated from tankyrase inhibitor-regulated naïve diabetic human iPSC potentiate efficient revascularization of ischemic retina
Author / Creator:Park, Tea Soon ; Zimmerlin, Ludovic ; Evans-Moses, Rebecca ; Thomas, Justin ; Huo, Jeffrey S. ; Kanherkar, Riya ; He, Alice ; Ruzgar, Nensi ; Grebe, Rhonda ; Bhutto, Imran ; Barbato, Michael ; Koldobskiy, Michael A. ; Lutty, Gerard ; Zambidis, Elias T.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-03, Vol.11 (1), p.1195-20, Article 1195
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Tankyrase inhibition preserves osteoarthritic cartilage by coordinating cartilage matrix anabolism via effects on SOX9 PARylation
Author / Creator:Kim, Sukyeong ; Han, Sangbin ; Kim, Yeongjae ; Kim, Hyeon-Seop ; Gu, Young-Ran ; Kang, Donghyun ; Cho, Yongsik ; Kim, Hyeonkyeong ; Lee, Jeeyeon ; Seo, Yeyoung ; Chang, Moon Jong ; Chang, Chong Bum ; Kang, Seung-Baik ; Kim, Jin-Hong
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-10, Vol.10 (1), p.4898-18, Article 4898
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Showing 1 to 20 of 741 results

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Structural basis of tankyrase activation by polymerization

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Whole proteome analysis of human tankyrase knockout cells reveals targets of tankyrase-mediated degradation

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RK‐287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model

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Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

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Novel insight into the function of tankyrase (Review)

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Tankyrase-targeted therapeutics: expanding opportunities in the PARP family

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Tankyrase Inhibitors Stimulate the Ability of Tankyrases to Bind Axin and Drive Assembly of β-Catenin Degradation-Competent Axin Puncta

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Tankyrase inhibition promotes endocrine commitment of hPSC-derived pancreatic progenitors

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Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors

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Multiple E3 ligases control tankyrase stability and function

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Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling

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Tankyrase inhibition sensitizes cells to CDK4 blockade

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Tankyrase represses autoinflammation through the attenuation of TLR2 signaling

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Crystal structure of a Tankyrase-Axin complex and its implications for Axin turnover and Tankyrase substrate recruitment

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3D-QSAR, Docking, ADME/Tox studies on Flavone analogs reveal anticancer activity through Tankyrase inhibition

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Tankyrase: a promising therapeutic target with pleiotropic action

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Tankyrase inhibition ameliorates lipid disorder via suppression of PGC-1α PARylation in db/db mice

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2-Phenylquinazolinones as dual-activity tankyrase-kinase inhibitors

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Vascular progenitors generated from tankyrase inhibitor-regulated naïve diabetic human iPSC potentiate efficient revascularization of ischemic retina

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Tankyrase inhibition preserves osteoarthritic cartilage by coordinating cartilage matrix anabolism via effects on SOX9 PARylation

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