Timeline of changes in spike conformational dynamics in emergent SARS-CoV-2 variants reveal progress...
Timeline of changes in spike conformational dynamics in emergent SARS-CoV-2 variants reveal progressive stabilization of trimer stalk with altered NTD dynamics
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England: eLife Science Publications, Ltd
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Language
English
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Publisher
England: eLife Science Publications, Ltd
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Contents
SARS-CoV-2 emergent variants are characterized by increased viral fitness and each shows multiple mutations predominantly localized to the spike (S) protein. Here, amide hydrogen/deuterium exchange mass spectrometry has been applied to track changes in S dynamics from multiple SARS-CoV-2 variants. Our results highlight large differences across vari...
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Full title
Timeline of changes in spike conformational dynamics in emergent SARS-CoV-2 variants reveal progressive stabilization of trimer stalk with altered NTD dynamics
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TN_cdi_doaj_primary_oai_doaj_org_article_e132c898884c4543b6bf006d6de5b0b7
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e132c898884c4543b6bf006d6de5b0b7
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.82584
