Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity
Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Cas9-based RNA-guided nuclease (RGN) has emerged to be a versatile method for genome editing due to the ease of construction of RGN reagents to target specific genomic sequences. The ability to control the activity of Cas9 with a high temporal resolution will facilitate tight regulation of genome editing processes for studying the dynamics of trans...
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Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity
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TN_cdi_doaj_primary_oai_doaj_org_article_e153d09732764e8691f331233833775d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e153d09732764e8691f331233833775d
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms12009
