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Conklin, Bruce R
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: BUR-CON, 2022, p.2273-2274
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Conklin, Bruce R
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: BUP-CON, 2021, p.2261-2261
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ArticlesPeer ReviewedFull Text
Generation of spatial-patterned early-developing cardiac organoids using human pluripotent stem cells
Author / Creator:Hoang, Plansky ; Wang, Jason ; Conklin, Bruce R ; Healy, Kevin E ; Ma, Zhen
Publisher:London: Nature Publishing Group UK
Journal title:Nature protocols, 2018-04, Vol.13 (4), p.723-737
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Human iPSC-based Cardiac Microphysiological System For Drug Screening Applications
Author / Creator:Mathur, Anurag ; Loskill, Peter ; Shao, Kaifeng ; Huebsch, Nathaniel ; Hong, SoonGweon ; Marcus, Sivan G. ; Marks, Natalie ; Mandegar, Mohammad ; Conklin, Bruce R. ; Lee, Luke P. ; Healy, Kevin E.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2015-03, Vol.5 (1), p.8883-8883, Article 8883
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ArticlesPeer ReviewedFull Text
CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells
Author / Creator:Liu, S. John ; Horlbeck, Max A. ; Cho, Seung Woo ; Birk, Harjus S. ; Malatesta, Martina ; He, Daniel ; Attenello, Frank J. ; Villalta, Jacqueline E. ; Cho, Min Y. ; Chen, Yuwen ; Mandegar, Mohammad A. ; Olvera, Michael P. ; Gilbert, Luke A. ; Conklin, Bruce R. ; Chang, Howard Y. ; Weissman, Jonathan S. ; Lim, Daniel A.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2017-01, Vol.355 (6320), p.39-39
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ArticlesPeer ReviewedFull Text
Systematic quantification of HDR and NHEJ reveals effects of locus, nuclease, and cell type on genome-editing
Author / Creator:Miyaoka, Yuichiro ; Berman, Jennifer R. ; Cooper, Samantha B. ; Mayerl, Steven J. ; Chan, Amanda H. ; Zhang, Bin ; Karlin-Neumann, George A. ; Conklin, Bruce R.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-03, Vol.6 (1), p.23549-23549, Article 23549
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ArticlesPeer ReviewedFull Text
Isolation of single-base genome-edited human iPS cells without antibiotic selection
Author / Creator:Miyaoka, Yuichiro ; Chan, Amanda H ; Judge, Luke M ; Yoo, Jennie ; Huang, Miller ; Nguyen, Trieu D ; Lizarraga, Paweena P ; So, Po-Lin ; Conklin, Bruce R
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2014-03, Vol.11 (3), p.291-293
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Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes
Author / Creator:Song, Michael ; Yang, Xiaoyu ; Ren, Xingjie ; Maliskova, Lenka ; Li, Bingkun ; Jones, Ian R. ; Wang, Chao ; Jacob, Fadi ; Wu, Kenneth ; Traglia, Michela ; Tam, Tsz Wai ; Jamieson, Kirsty ; Lu, Si-Yao ; Ming, Guo-Li ; Li, Yun ; Yao, Jun ; Weiss, Lauren A. ; Dixon, Jesse R. ; Judge, Luke M. ; Conklin, Bruce R. ; Song, Hongjun ; Gan, Li ; Shen, Yin
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2019-08, Vol.51 (8), p.1252-1262
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Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair
Author / Creator:Wienert, Beeke ; Nguyen, David N. ; Guenther, Alexis ; Feng, Sharon J. ; Locke, Melissa N. ; Wyman, Stacia K. ; Shin, Jiyung ; Kazane, Katelynn R. ; Gregory, Georgia L. ; Carter, Matthew A. M. ; Wright, Francis ; Conklin, Bruce R. ; Marson, Alex ; Richardson, Chris D. ; Corn, Jacob E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-04, Vol.11 (1), p.2109-2109, Article 2109
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ArticlesPeer ReviewedFull Text
Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity
Author / Creator:Nguyen, Duy P. ; Miyaoka, Yuichiro ; Gilbert, Luke A. ; Mayerl, Steven J. ; Lee, Brian H. ; Weissman, Jonathan S. ; Conklin, Bruce R. ; Wells, James A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-07, Vol.7 (1), p.12009-12009, Article 12009
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WikiPathways: pathway editing for the people
Author / Creator:Pico, Alexander R ; Kelder, Thomas ; van Iersel, Martijn P ; Hanspers, Kristina ; Conklin, Bruce R ; Evelo, Chris
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2008-07, Vol.6 (7), p.e184-e184
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ArticlesPeer ReviewedFull Text
Synthetic control of mammalian-cell motility by engineering chemotaxis to an orthogonal bioinert chemical signal
Author / Creator:Park, Jason S. ; Rhau, Benjamin ; Hermann, Aynur ; McNally, Krista A. ; Zhou, Carmen ; Gong, Delquin ; Weiner, Orion D. ; Conklin, Bruce R. ; Onuffer, James ; Lim, Wendell A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (16), p.5896-5901
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ArticlesPeer ReviewedFull Text
Integration of biological networks and gene expression data using Cytoscape
Author / Creator:Cline, Melissa S ; Smoot, Michael ; Cerami, Ethan ; Kuchinsky, Allan ; Landys, Nerius ; Workman, Chris ; Christmas, Rowan ; Avila-Campilo, Iliana ; Creech, Michael ; Gross, Benjamin ; Hanspers, Kristina ; Isserlin, Ruth ; Kelley, Ryan ; Killcoyne, Sarah ; Lotia, Samad ; Maere, Steven ; Morris, John ; Ono, Keiichiro ; Pavlovic, Vuk ; Pico, Alexander R ; Vailaya, Aditya ; Wang, Peng-Liang ; Adler, Annette ; Conklin, Bruce R ; Hood, Leroy ; Kuiper, Martin ; Sander, Chris ; Schmulevich, Ilya ; Schwikowski, Benno ; Warner, Guy J ; Ideker, Trey ; Bader, Gary D
Publisher:London: Nature Publishing Group UK
Journal title:Nature protocols, 2007-10, Vol.2 (10), p.2366-2382
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ArticlesPeer ReviewedFull Text
BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence
Author / Creator:Hayashi, Yohei ; Hsiao, Edward C. ; Sami, Salma ; Lancero, Mariselle ; Schlieve, Christopher R. ; Nguyen, Trieu ; Yano, Koyori ; Nagahashi, Ayako ; Ikeya, Makoto ; Matsumoto, Yoshihisa ; Nishimura, Ken ; Fukuda, Aya ; Hisatake, Koji ; Tomoda, Kiichiro ; Asaka, Isao ; Toguchida, Junya ; Conklin, Bruce R. ; Yamanaka, Shinya
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-11, Vol.113 (46), p.13057-13062
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ArticlesPeer ReviewedFull Text
Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultured over Different Spatial Scales
Author / Creator:Huebsch, Nathaniel ; Loskill, Peter ; Mandegar, Mohammad A. ; Marks, Natalie C. ; Sheehan, Alice S. ; Ma, Zhen ; Mathur, Anurag ; Nguyen, Trieu N. ; Yoo, Jennie C. ; Judge, Luke M. ; Spencer, C. Ian ; Chukka, Anand C. ; Russell, Caitlin R. ; So, Po-Lin ; Conklin, Bruce R. ; Healy, Kevin E.
Publisher:United States: Mary Ann Liebert, Inc
Journal title:Tissue engineering. Part C, Methods, 2015-05, Vol.21 (5), p.467-479
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Presenting and exploring biological pathways with PathVisio
Author / Creator:van Iersel, Martijn P ; Kelder, Thomas ; Pico, Alexander R ; Hanspers, Kristina ; Coort, Susan ; Conklin, Bruce R ; Evelo, Chris
Publisher:England: BioMed Central Ltd
Journal title:BMC bioinformatics, 2008-09, Vol.9 (1), p.399-399, Article 399
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Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors
Author / Creator:Kwon, Chulan ; Arnold, Joshua ; Hsiao, Edward C ; Taketo, Makoto M ; Conklin, Bruce R ; Srivastava, Deepak
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2007-06, Vol.104 (26), p.10894-10899
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Generating trunk neural crest from human pluripotent stem cells
Author / Creator:Huang, Miller ; Miller, Matthew L. ; McHenry, Lauren K. ; Zheng, Tina ; Zhen, Qiqi ; Ilkhanizadeh, Shirin ; Conklin, Bruce R. ; Bronner, Marianne E. ; Weiss, William A.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-01, Vol.6 (1), p.19727-19727, Article 19727
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Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
Author / Creator:Lahti, Anna L ; Kujala, Ville J ; Chapman, Hugh ; Koivisto, Ari-Pekka ; Pekkanen-Mattila, Mari ; Kerkelä, Erja ; Hyttinen, Jari ; Kontula, Kimmo ; Swan, Heikki ; Conklin, Bruce R ; Yamanaka, Shinya ; Silvennoinen, Olli ; Aalto-Setälä, Katriina
Publisher:England: The Company of Biologists Ltd
Journal title:Disease models & mechanisms, 2012-03, Vol.5 (2), p.220-230
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AlleleAnalyzer: a tool for personalized and allele-specific sgRNA design
Author / Creator:Keough, Kathleen C ; Lyalina, Svetlana ; Olvera, Michael P ; Whalen, Sean ; Conklin, Bruce R ; Pollard, Katherine S
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2019-08, Vol.20 (1), p.167-167, Article 167
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Conklin, Bruce R

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Conklin, Bruce R

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Generation of spatial-patterned early-developing cardiac organoids using human pluripotent stem cells

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Human iPSC-based Cardiac Microphysiological System For Drug Screening Applications

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CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells

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Systematic quantification of HDR and NHEJ reveals effects of locus, nuclease, and cell type on genome-editing

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Isolation of single-base genome-edited human iPS cells without antibiotic selection

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Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes

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Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair

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Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity

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WikiPathways: pathway editing for the people

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Synthetic control of mammalian-cell motility by engineering chemotaxis to an orthogonal bioinert chemical signal

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Integration of biological networks and gene expression data using Cytoscape

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BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence

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Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultured over Different Spatial Scales

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Presenting and exploring biological pathways with PathVisio

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Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors

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Generating trunk neural crest from human pluripotent stem cells

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Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture

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AlleleAnalyzer: a tool for personalized and allele-specific sgRNA design

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