The Future of GDNF in Parkinson's Disease
The Future of GDNF in Parkinson's Disease
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Publisher
Switzerland: Frontiers Research Foundation
Journal title
Language
English
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Publisher
Switzerland: Frontiers Research Foundation
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Scope and Contents
Contents
[...]preclinical and human clinical data clearly indicate that GFLs are, in fact, CNS dopaminergic trophic factors. [...]treatment with GFLs should promote survival of striatal dopamine (DA) innervation and thereby improve the motor symptoms of PD. So why have clinical trials utilizing this approach largely failed? [...]many intracellular processes...
Alternative Titles
Full title
The Future of GDNF in Parkinson's Disease
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TN_cdi_doaj_primary_oai_doaj_org_article_e1776ee5c46742d6bccf0fa8834b726c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e1776ee5c46742d6bccf0fa8834b726c
Other Identifiers
ISSN
1663-4365
E-ISSN
1663-4365
DOI
10.3389/fnagi.2020.593572
