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Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited ant...

Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited ant...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e19c792b6eed4c79a384d45bab80f5de

Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation

About this item

Full title

Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-06, Vol.12 (1), p.3993-3993, Article 3993

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Type II alveolar cells (AT2s) are critical for basic respiratory homeostasis and tissue repair after lung injury. Prior studies indicate that AT2s also express major histocompatibility complex class II (MHCII) molecules, but how MHCII expression by AT2s is regulated and how it contributes to host defense remain unclear. Here we show that AT2s expre...

Alternative Titles

Full title

Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e19c792b6eed4c79a384d45bab80f5de

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e19c792b6eed4c79a384d45bab80f5de

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-23619-6

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