Reversal of axonal growth defects in an extraocular fibrosis model by engineering the kinesin–microt...
Reversal of axonal growth defects in an extraocular fibrosis model by engineering the kinesin–microtubule interface
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Mutations in human β3-tubulin (
TUBB3
) cause an ocular motility disorder termed congenital fibrosis of the extraocular muscles type 3 (CFEOM3). In CFEOM3, the oculomotor nervous system develops abnormally due to impaired axon guidance and maintenance; however, the underlying mechanism linking
TUBB3
mutations to axonal growth defects re...
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Full title
Reversal of axonal growth defects in an extraocular fibrosis model by engineering the kinesin–microtubule interface
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TN_cdi_doaj_primary_oai_doaj_org_article_e1f2163676ed4f4f9ecb892722c22875
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e1f2163676ed4f4f9ecb892722c22875
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms10058
