Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson di...
Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity
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England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Parkinson disease (PD) is the second most common neurodegenerative disorder and the leading neurodegenerative cause of motor disability. Pathologic accumulation of aggregated alpha synuclein (AS) protein in brain, and imbalance in the nigrostriatal system due to the loss of dopaminergic neurons in the substantia nigra- pars compacta, are hallmark f...
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Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity
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TN_cdi_doaj_primary_oai_doaj_org_article_e23110f14d4a4b2fa31d3af3eb5018a9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e23110f14d4a4b2fa31d3af3eb5018a9
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-018-0554-9
