Pharmacokinetic and pharmacodynamic modeling of oral mitiglinide on glucose lowering in healthy Chin...
Pharmacokinetic and pharmacodynamic modeling of oral mitiglinide on glucose lowering in healthy Chinese volunteers
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Author / Creator
Liu, Shijia , Chen, Peidong , Zhao, Yang , Dai, Guoliang , Sun, Bingting , Wang, Yao , Ding, Anwei and Ju, Wenzheng
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Mitiglinide is a widely used agent for diabetic treatment. We established a pharmacokinetic-pharmacodynamic (PK-PD) model to illustrate the relationship between mitiglinide plasma concentration and its glucose lowering effects in healthy volunteers.
The volunteers participated in the test after the administration of a single dose of 10 mg mitigl...
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Full title
Pharmacokinetic and pharmacodynamic modeling of oral mitiglinide on glucose lowering in healthy Chinese volunteers
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TN_cdi_doaj_primary_oai_doaj_org_article_e2ad5d23479841b6ad51e9c97ba2cebf
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e2ad5d23479841b6ad51e9c97ba2cebf
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ISSN
2050-6511
E-ISSN
2050-6511
DOI
10.1186/s40360-017-0161-6