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Generation of functional ciliated cholangiocytes from human pluripotent stem cells

Generation of functional ciliated cholangiocytes from human pluripotent stem cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e2c37e554f8c4d829b4039f62abf625f

Generation of functional ciliated cholangiocytes from human pluripotent stem cells

About this item

Full title

Generation of functional ciliated cholangiocytes from human pluripotent stem cells

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-11, Vol.12 (1), p.6504-6504, Article 6504

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The derivation of mature functional cholangiocytes from human pluripotent stem cells (hPSCs) provides a model for studying the pathogenesis of cholangiopathies and for developing therapies to treat them. Current differentiation protocols are not efficient and give rise to cholangiocytes that are not fully mature, limiting their therapeutic applicat...

Alternative Titles

Full title

Generation of functional ciliated cholangiocytes from human pluripotent stem cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e2c37e554f8c4d829b4039f62abf625f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e2c37e554f8c4d829b4039f62abf625f

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-26764-0

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