Whole genome sequencing and imputation in isolated populations identify genetic associations with me...
Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Next-generation association studies can be empowered by sequence-based imputation and by studying founder populations. Here we report ∼9.5 million variants from whole-genome sequencing (WGS) of a Cretan-isolated population, and show enrichment of rare and low-frequency variants with predicted functional consequences. We use a WGS-based imputation a...
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Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits
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TN_cdi_doaj_primary_oai_doaj_org_article_e3b1f1065eac445cb9cf66847168b057
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e3b1f1065eac445cb9cf66847168b057
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2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms15606
