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Identification of small molecules that mitigate vincristine‐induced neurotoxicity while sensitizing...

Identification of small molecules that mitigate vincristine‐induced neurotoxicity while sensitizing...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e3e40089bb0343279b5f3003e28e87aa

Identification of small molecules that mitigate vincristine‐induced neurotoxicity while sensitizing leukemia cells to vincristine

About this item

Full title

Identification of small molecules that mitigate vincristine‐induced neurotoxicity while sensitizing leukemia cells to vincristine

Publisher

United States: John Wiley & Sons, Inc

Journal title

Clinical and translational science, 2021-07, Vol.14 (4), p.1490-1504

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Vincristine (VCR) is one of the most widely prescribed medications for treating solid tumors and acute lymphoblastic leukemia (ALL) in children and adults. However, its major dose‐limiting toxicity is peripheral neuropathy that can disrupt curative therapy. Peripheral neuropathy can also persist into adulthood, compromising quality of life of child...

Alternative Titles

Full title

Identification of small molecules that mitigate vincristine‐induced neurotoxicity while sensitizing leukemia cells to vincristine

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e3e40089bb0343279b5f3003e28e87aa

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e3e40089bb0343279b5f3003e28e87aa

Other Identifiers

ISSN

1752-8054

E-ISSN

1752-8062

DOI

10.1111/cts.13012

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