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The effect of calcium and magnesium on activity, immunogenicity, and efficacy of a recombinant N1/N2...

The effect of calcium and magnesium on activity, immunogenicity, and efficacy of a recombinant N1/N2...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e4321783a19a4370b86945991fe73acd

The effect of calcium and magnesium on activity, immunogenicity, and efficacy of a recombinant N1/N2 neuraminidase vaccine

About this item

Full title

The effect of calcium and magnesium on activity, immunogenicity, and efficacy of a recombinant N1/N2 neuraminidase vaccine

Publisher

London: Nature Publishing Group UK

Journal title

npj vaccines, 2021-04, Vol.6 (1), p.48-48, Article 48

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Despite the importance of immunity against neuraminidase (NA), NA content and immunogenicity are neglected in current influenza vaccines. To address this, a recombinant N1/N2 NA vaccine (NAV) was developed. Stability assays were used to determine optimal temperature and buffer conditions for vaccine storage. The effect of divalent cation-related en...

Alternative Titles

Full title

The effect of calcium and magnesium on activity, immunogenicity, and efficacy of a recombinant N1/N2 neuraminidase vaccine

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e4321783a19a4370b86945991fe73acd

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e4321783a19a4370b86945991fe73acd

Other Identifiers

ISSN

2059-0105

E-ISSN

2059-0105

DOI

10.1038/s41541-021-00310-x

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