Targeting the RdRp of Emerging RNA Viruses: The Structure-Based Drug Design Challenge
Targeting the RdRp of Emerging RNA Viruses: The Structure-Based Drug Design Challenge
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
The RNA-dependent RNA polymerase (RdRp) is an essential enzyme for the viral replication process, catalyzing the viral RNA synthesis using a metal ion-dependent mechanism. In recent years, RdRp has emerged as an optimal target for the development of antiviral drugs, as demonstrated by recent approvals of sofosbuvir and remdesivir against Hepatitis...
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Targeting the RdRp of Emerging RNA Viruses: The Structure-Based Drug Design Challenge
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TN_cdi_doaj_primary_oai_doaj_org_article_e4b054b28cfc4c97a2cc7fdc9d39a92a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e4b054b28cfc4c97a2cc7fdc9d39a92a
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules25235695
