Mutational landscape and in silico structure models of SARS-CoV-2 spike receptor binding domain reve...
Mutational landscape and in silico structure models of SARS-CoV-2 spike receptor binding domain reveal key molecular determinants for virus-host interaction
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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SARS-CoV-2, the causative agent of COVID-19 pandemic is a RNA virus prone to mutations. Formation of a stable binding interface between the Receptor Binding Domain (RBD) of SARS-CoV-2 Spike (S) protein and Angiotensin-Converting Enzyme 2 (ACE2) of host is pivotal for viral entry. RBD has been shown to mutate frequently during pandemic. Although, a...
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Mutational landscape and in silico structure models of SARS-CoV-2 spike receptor binding domain reveal key molecular determinants for virus-host interaction
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TN_cdi_doaj_primary_oai_doaj_org_article_e4db6bdee3604f1f99762479edb0766b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e4db6bdee3604f1f99762479edb0766b
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ISSN
2661-8850
E-ISSN
2661-8850,1471-2121
DOI
10.1186/s12860-021-00403-4