A cleavable peptide adapter augments the activity of targeted toxins in combination with the glycosi...
A cleavable peptide adapter augments the activity of targeted toxins in combination with the glycosidic endosomal escape enhancer SO1861
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Full title
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Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Treatment with tumor-targeted toxins attempts to overcome the disadvantages of conventional cancer therapies by directing a drug's cytotoxic effect specifically towards cancer cells. However, success with targeted toxins has been hampered as the constructs commonly remain bound to the outside of the cell or, after receptor-mediated endocytosis, are...
Alternative Titles
Full title
A cleavable peptide adapter augments the activity of targeted toxins in combination with the glycosidic endosomal escape enhancer SO1861
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e518259bb5c44aa697d0685ef707dd18
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e518259bb5c44aa697d0685ef707dd18
Other Identifiers
ISSN
1472-6750
E-ISSN
1472-6750
DOI
10.1186/s12896-024-00854-5
