In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers
In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers
About this item
Full title
Author / Creator
Watanabe, Sumiyo , Hayashi, Kotaro , Toh, Kazuko , Kim, Hyun Jin , Liu, Xueying , Chaya, Hiroyuki , Fukushima, Shigeto , Katsushima, Keisuke , Kondo, Yutaka , Uchida, Satoshi , Ogura, Satomi , Nomoto, Takahiro , Takemoto, Hiroyasu , Cabral, Horacio , Kinoh, Hiroaki , Tanaka, Hiroyoshi Y. , Kano, Mitsunobu R. , Matsumoto, Yu , Fukuhara, Hiroshi , Uchida, Shunya , Nangaku, Masaomi , Osada, Kensuke , Nishiyama, Nobuhiro , Miyata, Kanjiro and Kataoka, Kazunori
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Stabilisation of fragile oligonucleotides, typically small interfering RNA (siRNA), is one of the most critical issues for oligonucleotide therapeutics. Many previous studies encapsulated oligonucleotides into ~100-nm nanoparticles. However, such nanoparticles inevitably accumulate in liver and spleen. Further, some intractable cancers, e.g., tumou...
Alternative Titles
Full title
In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers
Authors, Artists and Contributors
Author / Creator
Hayashi, Kotaro
Toh, Kazuko
Kim, Hyun Jin
Liu, Xueying
Chaya, Hiroyuki
Fukushima, Shigeto
Katsushima, Keisuke
Kondo, Yutaka
Uchida, Satoshi
Ogura, Satomi
Nomoto, Takahiro
Takemoto, Hiroyasu
Cabral, Horacio
Kinoh, Hiroaki
Tanaka, Hiroyoshi Y.
Kano, Mitsunobu R.
Matsumoto, Yu
Fukuhara, Hiroshi
Uchida, Shunya
Nangaku, Masaomi
Osada, Kensuke
Nishiyama, Nobuhiro
Miyata, Kanjiro
Kataoka, Kazunori
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e56544229bd24572b3344d7cb418ce63
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e56544229bd24572b3344d7cb418ce63
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-09856-w
