Soluble CD13 induces inflammatory arthritis by activating the bradykinin receptor B1
Soluble CD13 induces inflammatory arthritis by activating the bradykinin receptor B1
About this item
Full title
Author / Creator
Tsou, Pei-Suen , Lu, Chenyang , Gurrea-Rubio, Mikel , Muraoka, Sei , Campbell, Phillip L , Wu, Qi , Model, Ellen N , Lind, Matthew E , Vichaikul, Sirapa , Mattichak, Megan N , Brodie, William D , Hervoso, Jonatan L , Ory, Sarah , Amarista, Camila I , Pervez, Rida , Junginger, Lucas , Ali, Mustafa , Hodish, Gal , O'Mara, Morgan M , Ruth, Jeffrey H , Robida, Aaron M , Alt, Andrew J , Zhang, Chengxin , Urquhart, Andrew G , Lawton, Jeffrey N , Chung, Kevin C , Maerz, Tristan , Saunders, Thomas L , Groppi, Vincent E , Fox, David A and Amin, M Asif
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
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More information
Scope and Contents
Contents
CD13, an ectoenzyme on myeloid and stromal cells, also circulates as a shed, soluble protein (sCD13) with powerful chemoattractant, angiogenic, and arthritogenic properties, which require engagement of a G protein-coupled receptor (GPCR). Here we identify the GPCR that mediates sCD13 arthritogenic actions as the bradykinin receptor B1 (B1R). Immuno...
Alternative Titles
Full title
Soluble CD13 induces inflammatory arthritis by activating the bradykinin receptor B1
Authors, Artists and Contributors
Author / Creator
Lu, Chenyang
Gurrea-Rubio, Mikel
Muraoka, Sei
Campbell, Phillip L
Wu, Qi
Model, Ellen N
Lind, Matthew E
Vichaikul, Sirapa
Mattichak, Megan N
Brodie, William D
Hervoso, Jonatan L
Ory, Sarah
Amarista, Camila I
Pervez, Rida
Junginger, Lucas
Ali, Mustafa
Hodish, Gal
O'Mara, Morgan M
Ruth, Jeffrey H
Robida, Aaron M
Alt, Andrew J
Zhang, Chengxin
Urquhart, Andrew G
Lawton, Jeffrey N
Chung, Kevin C
Maerz, Tristan
Saunders, Thomas L
Groppi, Vincent E
Fox, David A
Amin, M Asif
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e5e9835fa1944ab4a428208a7bd7d3dd
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e5e9835fa1944ab4a428208a7bd7d3dd
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI151827
