Clinicopathological features of 70 desmoid-type fibromatoses confirmed by β-catenin immunohistochemi...
Clinicopathological features of 70 desmoid-type fibromatoses confirmed by β-catenin immunohistochemical staining and CTNNB1 mutation analysis
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Desmoid-type fibromatosis (DF) is a locally aggressive neoplasm characterized by mutations in the CTNNB1 gene, which encodes the β-catenin protein. We reviewed 85 cases of DF and performed Sanger sequencing for detecting mutations in CTNNB1 and immunostaining for detecting β-catenin localization. We included 70 DF samples, of which 56 cases demonst...
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Clinicopathological features of 70 desmoid-type fibromatoses confirmed by β-catenin immunohistochemical staining and CTNNB1 mutation analysis
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TN_cdi_doaj_primary_oai_doaj_org_article_e62a32fc7479421b9a4cdeda7c7937c9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e62a32fc7479421b9a4cdeda7c7937c9
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0250619
