Triacylglycerol synthesis enhances macrophage inflammatory function
Triacylglycerol synthesis enhances macrophage inflammatory function
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Foamy macrophages, which have prominent lipid droplets (LDs), are found in a variety of disease states. Toll-like receptor agonists drive triacylglycerol (TG)-rich LD development in macrophages. Here we explore the basis and significance of this process. Our findings indicate that LD development is the result of metabolic commitment to TG synthesis...
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Triacylglycerol synthesis enhances macrophage inflammatory function
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TN_cdi_doaj_primary_oai_doaj_org_article_e66368483cc344ee9854c2ede5bf41d5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e66368483cc344ee9854c2ede5bf41d5
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-17881-3
