Alpha-B-Crystallin overexpression is sufficient to promote tumorigenesis and metastasis in mice
Alpha-B-Crystallin overexpression is sufficient to promote tumorigenesis and metastasis in mice
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England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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αB-Crystallin is a heat shock chaperone protein which binds to misfolded proteins to prevent their aggregation. It is overexpressed in a wide-variety of cancers. Previous studies using human cancer cell lines and human xenograft models have suggested potential tumor promoter (oncogene) roles for αB-Crystallin in a wide-spectrum of cancers.
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Alpha-B-Crystallin overexpression is sufficient to promote tumorigenesis and metastasis in mice
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TN_cdi_doaj_primary_oai_doaj_org_article_e79655148af34996b2fadab1d06fecb9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e79655148af34996b2fadab1d06fecb9
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ISSN
2162-3619
E-ISSN
2162-3619
DOI
10.1186/s40164-022-00365-z
