Association of genetic variation in the NR1H4 gene, encoding the nuclear bile acid receptor FXR, wit...
Association of genetic variation in the NR1H4 gene, encoding the nuclear bile acid receptor FXR, with inflammatory bowel disease
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Pathogenesis of inflammatory bowel diseases (IBD), ulcerative colitis (UC) and Crohn's disease (CD), involves interaction between environmental factors and inappropriate immune responses in the intestine of genetically predisposed individuals. Bile acids and their nuclear receptor, FXR, regulate inflammatory responses and barrier function in the in...
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Full title
Association of genetic variation in the NR1H4 gene, encoding the nuclear bile acid receptor FXR, with inflammatory bowel disease
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TN_cdi_doaj_primary_oai_doaj_org_article_e7bd0e42c66546c69a531c28ffaaa3db
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e7bd0e42c66546c69a531c28ffaaa3db
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ISSN
1756-0500
E-ISSN
1756-0500
DOI
10.1186/1756-0500-5-461
