Elevated CSF angiopoietin-2 correlates with blood-brain barrier leakiness and markers of neuronal in...
Elevated CSF angiopoietin-2 correlates with blood-brain barrier leakiness and markers of neuronal injury in early Alzheimer’s disease
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Breakdown of the neurovascular unit is associated with blood-brain barrier (BBB) leakiness contributing to cognitive decline and disease pathology in the early stages of Alzheimer’s disease (AD). Vascular stability depends on angiopoietin-1 (ANGPT-1) signalling, antagonised by angiopoietin-2 (ANGPT-2) expressed upon endothelial injury. We examined...
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Elevated CSF angiopoietin-2 correlates with blood-brain barrier leakiness and markers of neuronal injury in early Alzheimer’s disease
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TN_cdi_doaj_primary_oai_doaj_org_article_e810f28aac8941cab385eb1aa712f3ca
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e810f28aac8941cab385eb1aa712f3ca
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ISSN
2158-3188
E-ISSN
2158-3188
DOI
10.1038/s41398-023-02706-w
