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Empagliflozin inhibits Na+/H+ exchanger activity in human atrial cardiomyocytes

Empagliflozin inhibits Na+/H+ exchanger activity in human atrial cardiomyocytes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e817028f741049389f92939fa5c6a33a

Empagliflozin inhibits Na+/H+ exchanger activity in human atrial cardiomyocytes

About this item

Full title

Empagliflozin inhibits Na+/H+ exchanger activity in human atrial cardiomyocytes

Publisher

England: John Wiley & Sons, Inc

Journal title

ESC Heart Failure, 2020-12, Vol.7 (6), p.4429-4437

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Aims
Recent clinical trials have proven gliflozins to be cardioprotective in diabetic and non‐diabetic patients. However, the underlying mechanisms are incompletely understood. A potential inhibition of cardiac Na+/H+ exchanger 1 (NHE1) has been suggested in animal models. We investigated the effect of empagliflozin on NHE1 activity in human atr...

Alternative Titles

Full title

Empagliflozin inhibits Na+/H+ exchanger activity in human atrial cardiomyocytes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e817028f741049389f92939fa5c6a33a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e817028f741049389f92939fa5c6a33a

Other Identifiers

ISSN

2055-5822

E-ISSN

2055-5822

DOI

10.1002/ehf2.13024

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