Potassium channels Kv1.3 and KCa3.1 cooperatively and compensatorily regulate antigen-specific memor...
Potassium channels Kv1.3 and KCa3.1 cooperatively and compensatorily regulate antigen-specific memory T cell functions
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Voltage-gated Kv1.3 and Ca
2+
-dependent KCa3.1 are the most prevalent K
+
channels expressed by human and rat T cells. Despite the preferential upregulation of Kv1.3 over KCa3.1 on autoantigen-experienced effector memory T cells, whether Kv1.3 is required for their induction and function is unclear. Here we show, using Kv1.3-deficient...
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Full title
Potassium channels Kv1.3 and KCa3.1 cooperatively and compensatorily regulate antigen-specific memory T cell functions
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TN_cdi_doaj_primary_oai_doaj_org_article_e81be3fdce5148d7897e24bc26448b4f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e81be3fdce5148d7897e24bc26448b4f
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms14644
