Improving genetic prediction by leveraging genetic correlations among human diseases and traits
Improving genetic prediction by leveraging genetic correlations among human diseases and traits
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Genomic prediction has the potential to contribute to precision medicine. However, to date, the utility of such predictors is limited due to low accuracy for most traits. Here theory and simulation study are used to demonstrate that widespread pleiotropy among phenotypes can be utilised to improve genomic risk prediction. We show how a genetic pred...
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Full title
Improving genetic prediction by leveraging genetic correlations among human diseases and traits
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TN_cdi_doaj_primary_oai_doaj_org_article_e824d72f5f234577ab684601d5afb26b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e824d72f5f234577ab684601d5afb26b
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-02769-6
