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The tumor mutational landscape of BRCA2-deficient primary and metastatic prostate cancer

The tumor mutational landscape of BRCA2-deficient primary and metastatic prostate cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e8bd40b686474509a6110e6ca54a55c3

The tumor mutational landscape of BRCA2-deficient primary and metastatic prostate cancer

About this item

Full title

The tumor mutational landscape of BRCA2-deficient primary and metastatic prostate cancer

Publisher

London: Nature Publishing Group UK

Journal title

NPJ precision oncology, 2022-06, Vol.6 (1), p.39-39, Article 39

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Carriers of germline
BRCA2
pathogenic sequence variants have elevated aggressive prostate cancer risk and are candidates for precision oncology treatments. We examined whether
BRCA2
-deficient (
BRCA2
d
) prostate tumors have distinct genomic alterations compared with
BRCA2
-intact (
BRCA2
i
) tumors. Among 2536...

Alternative Titles

Full title

The tumor mutational landscape of BRCA2-deficient primary and metastatic prostate cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e8bd40b686474509a6110e6ca54a55c3

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e8bd40b686474509a6110e6ca54a55c3

Other Identifiers

ISSN

2397-768X

E-ISSN

2397-768X

DOI

10.1038/s41698-022-00284-6

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