An ensemble penalized regression method for multi-ancestry polygenic risk prediction
An ensemble penalized regression method for multi-ancestry polygenic risk prediction
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Great efforts are being made to develop advanced polygenic risk scores (PRS) to improve the prediction of complex traits and diseases. However, most existing PRS are primarily trained on European ancestry populations, limiting their transferability to non-European populations. In this article, we propose a novel method for generating multi-ancestry...
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An ensemble penalized regression method for multi-ancestry polygenic risk prediction
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TN_cdi_doaj_primary_oai_doaj_org_article_e9ada99664a547299a2de31c62d93bb4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e9ada99664a547299a2de31c62d93bb4
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-47357-7
