CSF1R antagonism limits local restimulation of antiviral CD8 + T cells during viral encephalitis
CSF1R antagonism limits local restimulation of antiviral CD8 + T cells during viral encephalitis
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Contents
Microglia are resident macrophages of the central nervous system (CNS) locally maintained through colony-stimulating factor 1 receptor (CSF1R) signaling. Microglial depletion via CSF1R inactivation improves cognition in mouse models of neuroinflammation, but limits virologic control in the CNS of mouse models of neurotropic infections by unknown me...
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Full title
CSF1R antagonism limits local restimulation of antiviral CD8 + T cells during viral encephalitis
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TN_cdi_doaj_primary_oai_doaj_org_article_ea5e7bfad2e14db4989c94771a93533e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea5e7bfad2e14db4989c94771a93533e
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-019-1397-4
