sTREM2 is associated with amyloid‐related p‐tau increases and glucose hypermetabolism in Alzheimer's...
sTREM2 is associated with amyloid‐related p‐tau increases and glucose hypermetabolism in Alzheimer's disease
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Author / Creator
Alzheimer's Disease Neuroimaging Initiative (ADNI) , the Alzheimer's Disease Neuroimaging Initiative (ADNI) , Biel, Davina , Suárez‐Calvet, Marc , Hager, Paul , Rubinski, Anna , Dewenter, Anna , Steward, Anna , Roemer, Sebastian , Ewers, Michael , Haass, Christian , Brendel, Matthias and Franzmeier, Nicolai
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
Microglial activation occurs early in Alzheimer's disease (AD) and previous studies reported both detrimental and protective effects of microglia on AD progression. Here, we used CSF sTREM2 to investigate disease stage‐dependent drivers of microglial activation and to determine downstream consequences on AD progression. We included 402 patients wit...
Alternative Titles
Full title
sTREM2 is associated with amyloid‐related p‐tau increases and glucose hypermetabolism in Alzheimer's disease
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ea66371c81c9496c92efbf79d69b23c9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea66371c81c9496c92efbf79d69b23c9
Other Identifiers
ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.202216987
