Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetes
Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetes
About this item
Full title
Author / Creator
McAllan, Liam , Baranasic, Damir , Villicaña, Sergio , Brown, Scarlett , Zhang, Weihua , Lehne, Benjamin , Adamo, Marco , Jenkinson, Andrew , Elkalaawy, Mohamed , Mohammadi, Borzoueh , Hashemi, Majid , Fernandes, Nadia , Lambie, Nathalie , Williams, Richard , Christiansen, Colette , Yang, Youwen , Zudina, Liudmila , Lagou, Vasiliki , Tan, Sili , Castillo-Fernandez, Juan , King, James W. D. , Soong, Richie , Elliott, Paul , Scott, James , Prokopenko, Inga , Cebola, Inês , Loh, Marie , Lenhard, Boris , Batterham, Rachel L. , Bell, Jordana T. , Chambers, John C. , Kooner, Jaspal S. and Scott, William R.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
DNA methylation variations are prevalent in human obesity but evidence of a causative role in disease pathogenesis is limited. Here, we combine epigenome-wide association and integrative genomics to investigate the impact of adipocyte DNA methylation variations in human obesity. We discover extensive DNA methylation changes that are robustly associ...
Alternative Titles
Full title
Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetes
Authors, Artists and Contributors
Author / Creator
Baranasic, Damir
Villicaña, Sergio
Brown, Scarlett
Zhang, Weihua
Lehne, Benjamin
Adamo, Marco
Jenkinson, Andrew
Elkalaawy, Mohamed
Mohammadi, Borzoueh
Hashemi, Majid
Fernandes, Nadia
Lambie, Nathalie
Williams, Richard
Christiansen, Colette
Yang, Youwen
Zudina, Liudmila
Lagou, Vasiliki
Tan, Sili
Castillo-Fernandez, Juan
King, James W. D.
Soong, Richie
Elliott, Paul
Scott, James
Prokopenko, Inga
Cebola, Inês
Loh, Marie
Lenhard, Boris
Batterham, Rachel L.
Bell, Jordana T.
Chambers, John C.
Kooner, Jaspal S.
Scott, William R.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ea82019d0abe4ca49fb6dbbbe87cd979
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea82019d0abe4ca49fb6dbbbe87cd979
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-38439-z
