Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pat...
Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Dominantly inherited missense mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common genetic cause of Parkinson's disease, but its normal physiological function remains unclear. We previously reported that loss of LRRK2 causes impairment of protein degradation pathways as well as increases of apoptotic cell death and inflammatory res...
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Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_eae55ca4de5c464da4cb33f6a3bb0326
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_eae55ca4de5c464da4cb33f6a3bb0326
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ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/1750-1326-7-2
