Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomi...
Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instability
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Topoisomerase 1, an enzyme that relieves superhelical tension, is implicated in transcription-associated mutagenesis and genome instability-associated with neurodegenerative diseases as well as activation-induced cytidine deaminase. From proteomic analysis of TOP1-associated proteins, we identify SMARCA4, an ATP-dependent chromatin remodeller; FACT...
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Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instability
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TN_cdi_doaj_primary_oai_doaj_org_article_eaf6c6b8283440a09e77451e98b651c1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_eaf6c6b8283440a09e77451e98b651c1
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms10549
