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Distinct subcellular localization of tau and alpha-synuclein in lewy body disease

Distinct subcellular localization of tau and alpha-synuclein in lewy body disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ebf4ff12a1204f5bb452069b9ead6560

Distinct subcellular localization of tau and alpha-synuclein in lewy body disease

About this item

Full title

Distinct subcellular localization of tau and alpha-synuclein in lewy body disease

Publisher

England: BioMed Central Ltd

Journal title

Acta neuropathologica communications, 2025-01, Vol.13 (1), p.14-13, Article 14

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Lewy bodies and neurofibrillary tangles, composed of α-synuclein (α-syn) and tau, respectively, often are found together in the same brain and correlate with worsening cognition. Human postmortem studies show colocalization of α-syn and tau occurs in Lewy bodies, but with limited effort to quantify colocalization. In this study, postmortem middle t...

Alternative Titles

Full title

Distinct subcellular localization of tau and alpha-synuclein in lewy body disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ebf4ff12a1204f5bb452069b9ead6560

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ebf4ff12a1204f5bb452069b9ead6560

Other Identifiers

ISSN

2051-5960

E-ISSN

2051-5960

DOI

10.1186/s40478-024-01913-w

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