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Effect of the micro-environment on α-synuclein conversion and implication in seeded conversion assay...

Effect of the micro-environment on α-synuclein conversion and implication in seeded conversion assay...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ec20df70754b41958c7ca86362854b74

Effect of the micro-environment on α-synuclein conversion and implication in seeded conversion assays

About this item

Full title

Effect of the micro-environment on α-synuclein conversion and implication in seeded conversion assays

Publisher

England: BioMed Central

Journal title

Translational neurodegeneration, 2020-01, Vol.9 (1), p.5-5, Article 5

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

α-Synuclein is a small soluble protein, whose physiological function in the healthy brain is poorly understood. Intracellular inclusions of α-synuclein, referred to as Lewy bodies (LBs), are pathological hallmarks of α-synucleinopathies, such as Parkinson's disease (PD) or dementia with Lewy bodies (DLB).
Understanding of the molecular basis as...

Alternative Titles

Full title

Effect of the micro-environment on α-synuclein conversion and implication in seeded conversion assays

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ec20df70754b41958c7ca86362854b74

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ec20df70754b41958c7ca86362854b74

Other Identifiers

ISSN

2047-9158

E-ISSN

2047-9158

DOI

10.1186/s40035-019-0181-9

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