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Pharmacokinetics of intranasal amiloride in healthy volunteers

Pharmacokinetics of intranasal amiloride in healthy volunteers

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ecb939b59a264699b045dde98bd00890

Pharmacokinetics of intranasal amiloride in healthy volunteers

About this item

Full title

Pharmacokinetics of intranasal amiloride in healthy volunteers

Publisher

United States: John Wiley & Sons, Inc

Journal title

Clinical and translational science, 2023-06, Vol.16 (6), p.1075-1084

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Anxiety and panic disorders are the most common mental illnesses in the United States and lack effective treatment options. Acid‐sending ion channels (ASICs) in the brain were shown to be associated with fear conditioning and anxiety responses and therefore are potential targets for treating panic disorder. Amiloride is an inhibitor of the ASICs in...

Alternative Titles

Full title

Pharmacokinetics of intranasal amiloride in healthy volunteers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ecb939b59a264699b045dde98bd00890

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ecb939b59a264699b045dde98bd00890

Other Identifiers

ISSN

1752-8054

E-ISSN

1752-8062

DOI

10.1111/cts.13514

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