Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C G...
Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus
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United States: Oxford University Press
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English
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United States: Oxford University Press
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Abstract
Recent genome-wide association studies (GWAS) have identified variants associated with high-density lipoprotein cholesterol (HDL-C) located in or near the ANGPTL8 gene. Given the extensive sharing of GWAS loci across populations, we hypothesized that at least one shared variant at this locus affects HDL-C. The HDL-C–associated variants...
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Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus
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TN_cdi_doaj_primary_oai_doaj_org_article_ecc7f25e27af4436b24b3848b1791633
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ecc7f25e27af4436b24b3848b1791633
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ISSN
2160-1836
E-ISSN
2160-1836
DOI
10.1534/g3.117.300088