Human Tau Expression Does Not Induce Mouse Retina Neurodegeneration, Suggesting Differential Toxicit...
Human Tau Expression Does Not Induce Mouse Retina Neurodegeneration, Suggesting Differential Toxicity of Tau in Brain vs. Retinal Neurons
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Switzerland: Frontiers Research Foundation
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English
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Switzerland: Frontiers Research Foundation
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The implication of the microtubule-associated protein (MAP) Tau in the ocular manifestations of Alzheimer's disease (AD) is elusive due to the lack of relevant animal model. However, signs of AD have been reported in the brain of transgenic mice expressing human Tau (hTau). To assess whether hTau is sufficient to induce AD pathogenesis in the retin...
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Human Tau Expression Does Not Induce Mouse Retina Neurodegeneration, Suggesting Differential Toxicity of Tau in Brain vs. Retinal Neurons
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TN_cdi_doaj_primary_oai_doaj_org_article_ed190b71a4c0458f9ac44eea44175172
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ed190b71a4c0458f9ac44eea44175172
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ISSN
1662-5099
E-ISSN
1662-5099
DOI
10.3389/fnmol.2018.00293
