Structural basis for hyperpolarization-dependent opening of human HCN1 channel
Structural basis for hyperpolarization-dependent opening of human HCN1 channel
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Hyperpolarization and cyclic nucleotide (HCN) activated ion channels are critical for the automaticity of action potentials in pacemaking and rhythmic electrical circuits in the human body. Unlike most voltage-gated ion channels, the HCN and related plant ion channels activate upon membrane hyperpolarization. Although functional studies have identi...
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Structural basis for hyperpolarization-dependent opening of human HCN1 channel
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TN_cdi_doaj_primary_oai_doaj_org_article_ed21ec411b92467f8993849f5cda3aa8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ed21ec411b92467f8993849f5cda3aa8
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2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-49599-x