High-throughput single nucleus total RNA sequencing of formalin-fixed paraffin-embedded tissues by s...
High-throughput single nucleus total RNA sequencing of formalin-fixed paraffin-embedded tissues by snRandom-seq
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Author / Creator
Xu, Ziye , Zhang, Tianyu , Chen, Hongyu , Zhu, Yuyi , Lv, Yuexiao , Zhang, Shunji , Chen, Jiaye , Chen, Haide , Yang, Lili , Jiang, Weiqin , Ni, Shengyu , Lu, Fangru , Wang, Zhaolun , Yang, Hao , Dong, Ling , Chen, Feng , Zhang, Hong , Chen, Yu , Liu, Jiong , Zhang, Dandan , Fan, Longjiang , Guo, Guoji and Wang, Yongcheng
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Formalin-fixed paraffin-embedded (FFPE) tissues constitute a vast and valuable patient material bank for clinical history and follow-up data. It is still challenging to achieve single cell/nucleus RNA (sc/snRNA) profile in FFPE tissues. Here, we develop a droplet-based snRNA sequencing technology (snRandom-seq) for FFPE tissues by capturing full-le...
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Full title
High-throughput single nucleus total RNA sequencing of formalin-fixed paraffin-embedded tissues by snRandom-seq
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TN_cdi_doaj_primary_oai_doaj_org_article_ed7b23c7d8264f029a6b0b5d4db3fef3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ed7b23c7d8264f029a6b0b5d4db3fef3
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-38409-5